The offensive line situation for both teams is a massive question mark, but we have to give someone the advantage, right?
The Panthers, when healthy, have the better offensive line. Unfortunately for them though, they're far from healthy. Starting guard Brady Christensen will miss the rest of the season with a biceps injury and starting offensive tackle Taylor Morton has been limited in practice all week with his own biceps injury. That leaves Ikem Ekwonu, Nash Jensen, rookie Chandler Zavala, Bradley Boseman, and potentially Ricky Lee or Calvin Throckmorton (former Saints lineman) as the week two starters. That's flat out not going to cut it against a Saints' defense that mustered up three sacks against a stout Titans offensive line last week.
The Saints have a rather healthy offensive line, they just vastly underperformed last week. Trevor Penning really struggled to protect Carr which led the Carr getting roughed up quite a bit. Penning was the major red flag, but James Hurst, Ryan Ramczyk, Erik McCoy, and Cesar Ruiz held their ground for the most part. The Titans also have a very good defensive line (top three in the league in my opinion), so they should be able to fare a tad bit better in week two.
All in all, the advantage goes to New Orleans. The offensive lines will be interesting to watch for both teams on Monday Night, but in this scenario, the upper hand has to go to the healthier squad.