Buccaneers vs. Saints prediction, odds, spread, injuries, trends for NFL Week 4

A full betting preview for the 2-1 New Orleans Saints and 2-1 Tampa Bay Buccaneers a Week 4 NFC South clash.
New Orleans Saints quarterback Jameis Winston (2)
New Orleans Saints quarterback Jameis Winston (2) / Jeff Hanisch-USA TODAY Sports

The NFC South is somehow one of the most competitive divisions in the NFL so far.

The Carolina Panthers are out of it at 0-3, but the three other teams are all 2-1 including the Tampa Bay Buccaneers, who lost their first game of the year on Monday Night Football to the Eagles, and the New Orleans Saints.

The Saints looked like they were cruising to 3-0 after three quarters on Sunday, but they blew a 17-0 fourth quarter lead and the 18-17 loss wasn’t their only loss of the day. Derek Carr left the game with a shoulder injury and could miss Week 4. 

For a look around the league in Week 4 check out BetSided NFL betting expert Iain MacMillan’s “Road to 272” where he bets every game of the season. If you’re betting any or every NFL game this week, you can do it with this great promo from the FanDuel Sportsbook. Just sign up below and bet $5 to claim $200 in bonus bets, win or lose. 

Now, let’s take a look at the odds for this matchup. 

Buccaneers vs. Saints odds, spread and total 

Saints vs. Buccaneers Betting Trends

  • Saints are 0-2-1 ATS
  • The UNDER is 3-0 in Saints games
  • Buccaneers are 2-1 ATS
  • The UNDER is 2-1 in Buccaneers games

Buccaneers vs. Saints injury reports

Buccaneers injury report

  • Calijah Kancey - DL - Questionable (calf)
  • Carlton Davis III - CB - Ques Sun (toe)
  • SirVocea Dennis - LB - Questionable (hamstring)
  • Jamel Dean - CB - Ques Sun (shoulder)
  • Chase Edmonds - RB - Early Nov (knee)

Saints injury report

  • Alvin Kamara - RB - Eligible Sunday (suspension)
  • Foster Moreau - TE - Questionable (ankle)
  • Paulson Adebo - CB - Questionable (hamstring)
  • Caesar Ruiz - C - Questionable (concussion)
  • Derek Carr - QB - Questionable (shoulder)
  • Jamaal Williams - RB - IR (hamstring)
  • Marcus Maye - S - Elig Week 6 (suspension)
  • Payton Turner - DE - IR (toe)
  • Tre’Quan Smith - WR - IR (groin)

Buccaneers vs. Saints how to watch

  • Date: Sunday, October 1
  • Time: 1:00 PM EST
  • Venue: Caesars Superdome
  • How to Watch (TV): FOX
  • Buccaneers Record: 2-1
  • Saints Record: 2-1

Buccaneers vs. Saints key players to watch


Rachaad White, RB: The Bucs have not been able to run the ball at all this year. White is averaging 3.1 yards per carry and 50.0 yards per game. Most of that isn’t his fault, there just aren’t any lanes to run through. 


Jameis Winston, QB: It’s possible that Derek Carr plays this weekend, but feels unlikely with his sprained AC joint. Winston is a good option as a backup and will get to face his former team. Winston went 10-for-16 for 101 yards in relief of Carr on Sunday, but allowed Green Bay to pull off a fourth quarter comeback win. 

Buccaneers vs. Saints prediction and pick

The New Orleans Saints may have lost some talent from their roster over the past couple years and they lost some offensive creativity with Sean Payton’s departure, but they still have Dennis Allen, so they still have a good defense. It seems like Allen is enough to have one of the best groups in the NFL. 

So far this season, the Saints defense is top 10 in yards per game, yards per play, rushing yards, passing yards, completion percentage and yards per attempt. That unit is only allowing 16.7 points per game which is sixth best in the NFL. 

It helps that New Orleans has only faced Ryan Tannehill, Bryce Young and Jordan Love, but it’s not going to get much tougher against Baker Mayfield this week. The Bucs are only averaging 19.3 points per game. Tampa Bay’s defense is a solid unit too despite its lack of depth at cornerback. 

In the Saints last 10 games the under is 9-1 and since Dennis Allen took over as head coach the under is 14-6. That will be my play in Week 4. 

Follow all Josh Yourish’s bets HERE

Game odds refresh periodically and are subject to change